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ea0037gp.13.06 | Diabetes and obesity – Translational cardiovascular and obesity | ECE2015

Effects of testosterone replacement therapy on lean body mass, total fat mass, and insulin sensitivity in aging men with type 2 diabetes - a randomised, double-blinded, placebo-controlled trial

Magnussen Line Velling , Glintborg Dorte , Hermann Pernille , Hougaard David M , Hojlund Kurt , Andersen Marianne S

Lowered testosterone levels may be observed in up to 50% of ageing men with type 2 diabetes (T2D). Testosterone replacement therapy (TRT) increases lean body mass in men with lowered testosterone levels and T2D, but the effect of TRT on glucose metabolism has not been evaluated by euglycemic hyperinsulinemic clamp.We used gold standard methods to evaluate the effect of TRT on body composition, insulin sensitivity, and oxidative metabolism in men with T2D...

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Effects of testosterone replacement therapy on lean body mass, total fat mass, and insulin sensitivity in aging men with type 2 diabetes - a randomised, double-blinded, placebo-controlled trial

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